NSCLC Value Model
A Flexible Modeling Platform for Lung Cancer
Oncology is an area of immense clinical need and a primary driver of healthcare spending, making it a prime target for assessment of the value of available medical interventions. Of the many forms of cancer, lung cancer is the leading cause of cancer-related deaths worldwide.(1) The American Cancer Society estimates that of the 1,735,000 new cancer cases in the U.S. in 2018, 13.5% will be lung cancer. NSCLC accounts for an estimated 85% of lung cancer cases and comprises adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.(2)
The Center for Innovation & Value Research’s first oncology-specific Open-Source Value Platform (OSVP) model focuses on non-small cell lung cancer (NSCLC). Specifically, our NSCLC model examines the value of sequential treatment strategies for patients with epidermal growth factor receptor positive (EGFR+) NSCLC, which accounts for 8% of new NSCLC cases.(3)
How Does Our NSCLC Model Work?
Our NSCLC model is an open-source simulation model that decision-makers can use to assess the value of different sequences of treatment for non-small cell lung cancer (NSCLC). Specifically, NSCLC model provides information on expected health benefits, risks and costs for patients with EGFR+ NSCLC.
Incorporating the Patient Perspective
See how we worked with patients and other stakeholders to build Version 1 of our RA Value Tool.
Application in the Real World
Learn about the mechanics of our RA model, which serves as the engine for our RA Value Tool, and see specific examples of how it can be used.
Review Our RA Model Detailed Methodology
Click here to learn more about the technical details on how our RA model is constructed.
Get Started with Our NSCLC Value Model
Our NSCLC Value Tool is an easy-to-use web-based interface designed to help healthcare decision-makers use the NSCLC model to evaluate treatment strategies for EGFR+ NSCLC.
The NSCLC Value Model can be accessed by installing the NSCLC Model R Package.
Source Code for the NSCLC model is also available on GitHub.
RESOURCES
Our NSCLC model, part of the Open-Source Value Project (OSVP), was created, developed, and is owned by Precision Health Economics LLC (now PRECISIONheor) and is licensed to the Center for Innovation & Value Research for its use in connection with redefining how value of pharmaceutical treatment is assessed. In keeping with the Center for Innovation & Value Research’s philosophy, this includes sharing and distribution of source code, data and parameter inputs, and any additional materials and technical documentation supporting open use, distribution, and adaptation of the model with attribution to the model developers.
In addition, any work performed by the Center for Innovation & Value Research based on the NSCLC model is conducted as part of the OSVP and is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license visit: https://creativecommons.org/licenses/by/4.0/.