This IVI Value Blueprint summarizes an October 2022 expert roundtable that identified and prioritized key attributes needed to better define and measure innovation in health technology assessment (HTA)., emphasizing patient-centered, long-term, and societal value elements. The report highlights gaps in data and methods—particularly for scientific spillover, real-option value, and broader societal impacts—and outlines research priorities to guide future methodological development and a Call for Papers.